General Information

  • ID:  hor002732
  • Uniprot ID:  F5XVE9
  • Protein name:  Ci-NTLP-6
  • Gene name:  ci-nt-B
  • Organism:  Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SRHPKLYFPGIV
  • Length:  12(109-120)
  • Propeptide:  MSSTTLMGRVGILIVVIICLQQQQLTQGIPLSEEIQELLKNRVVSNEADRSDISDYYDQGLGEEIGDSSELFLWFIYKSLLADLKKTGKNNVEVEQRNKLLYPSVIKKSRHPKLYFPGIVKRSVQSGTENKQTDETTF
  • Signal peptide:  MSSTTLMGRVGILIVVIICLQQQQLTQG
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-F5XVE9-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002732_AF2.pdbhor002732_ESM.pdb

Physical Information

Mass: 161006 Formula: C68H104N18O15
Absent amino acids: ACDEMNQTW Common amino acids: P
pI: 10.45 Basic residues: 3
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: -16.67 Boman Index: -1087
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 89.17
Instability Index: 3369.17 Extinction Coefficient cystines: 1490
Absorbance 280nm: 135.45

Literature

  • PubMed ID:  21467196
  • Title:  Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides